Clinical Efficacy of an Automated High-Sensitivity C-Reactive Protein Assay

Clinical efficacy of an automated high-sensitivity C-reactive protein assay.

BACKGROUND Prospective studies have shown that C-reactive protein (CRP) can be used to predict risk of future cardiovascular events. High-sensitivity methods for CRP (hs-CRP) measurement are needed for this purpose. METHODS We compared the clinical efficacy of an automated and commercially available latex-enhanced assay (Latex) for hs-CRP (Dade Behring) to a validated in-house ELISA, previous...

Evaluation of four automated high-sensitivity C-reactive protein methods: implications for clinical and epidemiological applications.

BACKGROUND C-reactive protein (CRP) can provide prognostic information about the risk of developing atherosclerotic complications in apparently healthy patients. This new clinical application requires quantification of CRP concentrations below those traditionally measured in the clinical laboratory. METHODS The Dade Behring BN II, the Abbott IMx, the Diagnostic Products Corporation IMMULITE, ...

High-Sensitivity C-Reactive Protein and Cancer

BACKGROUND High-sensitivity C-reactive protein (hs-CRP) is a commonly used inflammatory marker. The association between hs-CRP and cancer is less consistent than that between hs-CRP and cardiovascular diseases. This study explored the association between hs-CRP and cancer, using a large database of Korean health examination records. METHODS A total of 80,781 Koreans who visited the health pro...

High-sensitivity C-reactive protein methods examined.

Steatosis DeLIVERs high-sensitivity C-reactive protein.

Nonalcoholic fatty liver disease is characterized by excess accumulation of lipids within parenchymal cells of the liver (ie, hepatocellular steatosis) in the absence of excessive ethanol consumption. Fatty liver disease is widely considered to be the hepatic manifestation of metabolic syndrome and is estimated to occur in more than 25% of the Western population.1 Nonalcoholic fatty liver disea...